SQUAMOUS CELL CARCINOMA Skvamoznim karcinomom

SCC is when there is abnormal growth of the superficial cells of the skin/epidermis. SCC je, ko je nenormalna rast površinskih celic kože / povrhnjice. These cells are referred to keratinocytes, which form the top layer of your skin, and form the "dust" in your house once they fall off. Te celice so navedene keratinocytes, ki sestavljajo vrhnjo plast kožo, in tvorijo "prah" v tvojo hišo, ko odpade. Similar causes and treatments as with basal cell carcinoma (BCC). Podobnih vzrokov in zdravljenje, kot je s karcinoma bazalnih celic (BCC).

• Referred to as a neoplasm (new growth) of keratinocytes Navedena kot neoplazme (novo rast) z dne keratinocytes

• Risk Factors for Squamous Cell Skin Cancer Dejavniki tveganja za kožnega raka skvamoznih celic

  • males moški

  • elderly or over 50 starejših ali več kot 50

  • sun tanners + tanning salon customers ne tanners + strojenju salon strankam

  • light skinned individuals who also have light hair (eg blonde) svetlo kožo posameznikov, ki imajo prav tako lahka las (npr. blondinka)

    Causes of Squamous Cell Skin Cancer Vzroki za skvamoznih celic kožnega raka

• Sun Exposure/UV radiation, UVB, high energy sun rays, that alter the genetic make-up of the keratinocyte cells, causing them to grow abnormally and more rapidly Ne izpostavljenosti / UV sevanja, UVB, visoko energetsko ne žarke, ki spreminjajo genetsko zasnovo za keratinocitni celic, kar povzroči njihovo nenormalno rast in več hitro

• Can also be caused by mutagens, such as heavy metal exposure (eg arsenic) and tar Lahko tudi mutagenim snovem, ki jih povzroča, kot so težke kovine, z izpostavljenostjo (npr. arzen) in katrana

Appearance of squamous cell cancer under the microscope after a biopsy of the tissue from a patient. Videz rakom skvamoznih celic pod mikroskopom po biopsiji na tkivo od bolnika. Abnormal, cancerous cells are dark purple, displaying loose and abundant DNA in comparison to normal, nonreplicating cells. Nenormalno, rakavih celic, so temno vijolične, prikazanega v razsutem stanju in bogatih DNA v primerjavi z normalno, nonreplicating celic.

• Appearance of Squamous Cell Skin Cancer Pojav kožnega raka skvamoznih celic

• a red nodule or plaque, with scales on its surface rdeča nodule ali ploščica, z lestvic na njeni površini

• usually turns into an ulcer on the skin običajno pretvori v razjeda na koži

• can also have crusting, which is when the skin "weeps" blood components slowly onto the skin which dry quickly forming a crust lahko tudi "crust" obdelavi, ki je, ko je koža "joka" komponent krvi, ki se počasi na suho kožo, ki hitro tvori "crust"

Effects sites of Sun Expsure, such as: Učinki lokacij ne Expsure, kot so:

• face obraz

• back of the neck tilniku

• scalp lasišča

• nose nos

• ears ušesa

• anywhere where there has been a lot of skin exposure (eg hands, forearms) povsod, kjer je bilo veliko izpostavljenost kože (npr. roke, podlahti)

  Treatments for Squamous Cell Skin Cancer Skvamoznih celic za zdravljenje kožnega raka

• Squamous cell carcinomas grow much more rapidly than basal cell carcinomas, therefore: Skvamoznim karcinomov raste veliko hitreje kot karcinomov bazalnih celic, zato:

• surgical removal kirurška odstranitev

• may need closure through skin flaps or a skin graft if lesion was large morda potrebovali zapiranja loput preko kože ali kožne lezije, če presadka je bilo veliko

• After treatment, will need to see doctor yearly to screen for any recurrence Po zdravljenju, bo treba za prikaz na zaslonu zdravnika letno, za katero koli ponovitev

• about 80% cure rate približno 80% pozdravi stopnja

• 10% metastasize - therefore important to seek treaetment as early as possible 10% metastasize - zato pomembno poiskati treaetment čim prej